Sarcoglycan Deficient Muscular Dystrophy (SDMD)
SDMD (Sarcoglycan Deficient Muscular Dystrophy)
SDMD is a form of limb-girdle muscular dystrophy associated with a mutation in a muscle sarcoglycan gene has been identified in young miniature Dachshunds from Australia, South Africa, and the US. Clinical signs, first noted at approximately 6 months of age were variable and included exercise intolerance, stiff gait, myoglobinuria and dysphagia. The serum CK activity was markedly and persistently elevated. Histopathology of muscle biopsies showed a dystrophic phenotype and immunofluorescent stainings showed all sarcoglycan proteins were markedly decreased or absent.
Contact Details
Dachshund Club of Victoria Inc.
Phone : +61352348224
Email : [email protected]